I once tried to do a campaign as the SPQR. However, I was a serious noob back then and I couldn't do it without a ton of cheats. I got bored after I had conquered Gaul.
I did a scipii campaign more recently, in which I tried to be historically accurate with the dates. I failed. To say the least, the Carthaginians attacked me too early for the start of the First Punic War, and I had conquered Carthage by 241BC - the historical end of the First Punic War, a hundred years before the historical sack of the city. So I think historical accuracy in this game is impossible.
[This message has been edited by Edorix (edited 06-02-2009 @ 01:05 PM).]